IMPACT OF HABITATION CONDITIONS ON METABOLISM IN THE MUSCLES, LIVER, AND GONADS OF DIFFERENT SEX AND AGE GROUPS OF BREAM

Impact of habitation conditions on metabolism in the muscles, liver, and gonads of different sex and age groups of bream

Impact of the factors of the aquatic environment is an inevitable aspect of the life of fish as poikilothermic animals and provokes responses in their organisms.The study focused on determining peculiarities in the composition of the metabolic products in the tissues of different age and sex groups of common bream Abramis brama (L.) depending on th

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Identification of genes from ten oncogenic pathways associated with mortality and disease progression in glioblastoma

Glioblastoma multiforme (GBM) is the most malignant brain tumor with an extremely poor prognosis.The Cancer Genome Atlas (TCGA) database has been used to confirm the roles played by 10 canonical oncogenic signaling pathways in various cancers.The purpose of this study was to evaluate the expression of genes in these 10 canonical oncogenic signaling

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First presentation of a frameshift mutation in the SETD2 gene of a juvenile psammomatoid ossifying fibroma (JPOF) associated with an aneurysmal bone cyst

Abstract Background The rarity of juvenile psammomatoid ossifying fibroma (JPOF) and lack of cytogenetic studies prompted us to report a novel SETD2 gene mutation in a benign odontogenic tumour.Case presentation A 21-year-old man presented with a hard, expanded mandibular cortex.Computed tomography revealed multilocular radiopacity in the mandible;

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Emerging applications of extracellular vesicles in tumor therapy

Abstract Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers.Their h22a4 transmission physical, chemical and biological characteristics distinguish them as unique carriers with specific pharmacokinetic, circulating metabolic, and biodistribution patterns in the delivery of therapeutic cargoes.They are

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Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation

Abstract Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis.Both genetic and lifestyle factors, particularly diet and nobivac 1-dappv for puppies nutrition, contribute to its etiology.Folate

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